Born in 1993, he received his first horn lessons at the age of 4. He received his further education as a young student with Prof. Joachim Pöltl in Düsseldorf and as a student with Prof. Paul van Zelm in Cologne. He received further impulses from Hermann Baumann, Erich Penzel, Prof. Christian Lampert and Froydis Ree Wekre. Marc Gruber has won several prizes in the "Jugend Musiziert" competition, and in 2010 he also received a scholarship from the "International Music Academy Frankfurt for Modern Music". He also won the South German Chamber Music Competition and was the first brass player ever to win the "Debut um elf" prize. Furthermore, he has been a scholarship holder of the renowned Mozart Society Dortmund since 2013 and was a prize winner at the Lions European Musical Competition in 2014. In 2016 he won 2nd prize at the ARD International Music Competition as well as the Brüder-Busch Special Prize and the Audience Prize.
He has also made numerous solo appearances, including with the Bavarian Radio Symphony Orchestra, the Düsseldorf Symphony Orchestra, the Dortmund Orchestra Centre and the Würtemberg Philharmonic Orchestra Reutlingen. With the latter orchestra he also released his debut CD as a soloist in 2014, featuring the Sinfonia Concertante by Wolfgang Amadeus Mozart for four solo winds and orchestra. As a chamber music partner, Marc Gruber has performed with renowned ensembles and soloists such as the Schumann Quartet, the Linos Ensemble, the Mannheim String Quartet, HR-Brass and as a permanent member of the Monet Wind Quintet at national and international festivals. He did this at the Ludwigsburg Schlossfestspiele and the Festspiele Mecklenburg-Vorpommern, among others. With the Monet Wind Quintet he became a scholarship holder and special prize winner of the German Music Competition in 2016.
Marc Gruber gained orchestral experience early on in various youth orchestras, such as the Landesjugendorchester NRW, the Bundesjugendorchester, the Junge Deutsche Philharmonie and the European Union Youth Orchestra. Here, tours led him through China, Japan, Korea and all of Europe. From 2014 to 2016 he was the youngest solo hornist ever in the Bonn Beethoven Orchestra and has been employed in this position by the Hessian Radio Symphony Orchestra since April 2016.